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Centrifuge-Free Bone Marrow Aspirate Harvest for Orthopaedic Applications
Oyadomari, Sarah; Wang, Dean; Ranawat, Anil
Arthroscopy Techniques, Volume 0, Issue 0, 103721
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Different methods of bone marrow harvesting influence cell characteristics and purity, affecting clinical outcomes.
Caradonna, Eugenio et al.
JVS-Vascular Science, Volume 4, 100130
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MSC's, HSC's, TNC's, MNC's, Purity and Contaminants
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Pearl, A., Saleh, K., Korsog, D., & Mundt, J. (2023). Bone Marrow Aspirate Concentrate Chondroplasty to Delaying Need for Total Knee Arthroplasty: A Retrospective Review of a Veteran Cohort. Regenerative Medicine, 18(11), 833–838.
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MSC's, HSC's, Mononuclear Cells, CFU's, TNC's
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Osteo-core plasty: minimally invasive approach for subchondral pathologies
Herman, Katarzyna et al.
Journal of Cartilage & Joint Preservation, Volume 3, Issue 1, 100101
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Marrow Cellution BMA + Bone Dowel (PercuGraft)
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Tsitsilianos, N., Shirazi, Z., Lu, J., & Singh, J. R. (2022). Bone marrow aspirate injection for osteoarthritis of the hip: A pilot study. Interventional Pain Medicine, 1(4), 100163. https://doi.org/10.1016/j.inpm.2022.100163
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Kuebler, D., Schnee, A., Moore, L., Kouri, J., McLaughlin, A., Hanson, R., Kuebler, P., Dallo, I., & Gobbi, A. (2022). Short-term efficacy of using a novel low-volume bone marrow aspiration technique to treat knee osteoarthritis: A retrospective cohort study. Stem Cells International. https://doi.org/10.1155/2022/5394441
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MSC's, HSC's, VAS and WOMAC scores
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Dallo, I., D’Ambrosi, R., Szwedowski, D., Mobasheri, A., & Gobbi, A. (2022). Minimally invasive cell-based therapy for symptomatic bone marrow lesions of the knee: A prospective clinical study at 1 year. Stem Cells and Development, 31(15-16). https://doi.org/10.1089/scd.2021.0283
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Marrow Cellution BMA + PercuGraft Bone Dowel
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MSC's, Growth Factors and Cytokines
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Gobbi, A., Morales, M., & Valsecchi, G. (2022). Biologic knee arthroplasty in 360 degrees for early osteoarthritis treatment. Medical Research Archives, 10(3).
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Marrow Cellution BMA + PercuGraft Bone Dowel
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MSC's, Growth Factors and Cytokines
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Viganò, M., Ragni, E., Di Matteo, B., Gambaro, F. M., Perucca Orfei, C., Spinelli, G., Colombini, A., di Girolamo, L., & Kon, E. (2021). A single-step, centrifuge-free method to harvest bone marrow highly concentrated in mesenchymal stem cells: Results of a pilot trial. International Orthopaedics, 46(1), 391–400.
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Bone Marrow Cell Harvesting
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Dwyer, T., Hoit, G., Lee, A., Watkins, E., Henry, P., Leroux, T., Veillette, C., Theodoropoulos, J., Ogilvie-Harris, D., & Chahal, J. (2021). Injection of bone marrow aspirate for glenohumeral joint osteoarthritis: A pilot randomized control trial. Arthroscopy, Sports Medicine, and Rehabilitation, 3(5), e1431–e1440.
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Gobbi, A., Dallo, I., Frank, R. M., Bradsell, H., Saenz, I., & Murrel, W. (2021). A review of bone marrow lesions in the arthritic knee and description of a technique for treatment. Journal of Cartilage and Joint Preservation, 1(3), 100021.
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Marrow Cellution BMA + PercuGraft Bone Dowel
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Varady, N. H., Cate, G., Barghi, A., Yakin, D., Ylanan, R. C., & Arnold, C. A. (2020). Positive early clinical outcomes of bone marrow aspirate concentrate for osteoarthritis using a novel fenestrated trocar. Journal of Cartilage and Joint Preservation, 27(5), 1627–1634.
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Prodromos, C., & Finkle, S. (2020). Autologous Biologic Treatment with Fat, Bone Marrow Aspirate and Platelet Rich Plasma Is an Effective Alternative to Total Knee Arthroplasty for Patients with Moderate Knee Arthrosis. Medicines, 7(6), 37. https://doi.org/10.3390/medicines7060037
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Marrow Cellution BMA + PRP + Adipose
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MSC's, Platelets, Adipose-Derived Cells
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Colberg, R. E., Jurado Vélez, J. A., Walsh, K. P., & Fleisig, G. (2020). Short-term outcomes after pure bone marrow aspirate injection for severe knee osteoarthritis: A case series. Regenerative Medicine, 15(18), 1851–1859.
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MSC's, Mononuclear Cells, HSC's
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Wells, K., Klein, M., Hurwitz, N., Santiago, K., Cheng, J., Abutalib, Z., Beatty, N., & Lutz, G. (2020). Cellular and clinical analyses of autologous bone marrow aspirate injectate for knee osteoarthritis: A pilot study. Pain Medicine, 21(6), 12429.
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Bieri, M., Said, E., Antonini, G., Dickerson, D., Tuma, J., Bartlett, C. E., Patel, A. N., & Gershman, A. (2020). Phase I and registry study of autologous bone marrow concentrate evaluated in PDE5 inhibitor refractory erectile dysfunction. Journal of Translational Medicine, 18, Article 24.
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Scarpone, M., Kuebler, D., Chambers, A. et al. Isolation of clinically relevant concentrations of bone marrow mesenchymal stem cells without centrifugation. J Transl Med 17, 10 (2019). https://doi.org/10.1186/s12967-018-1750-x
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Bone Marrow Cell Harvesting
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Henderson, R. G., & Colberg, R. E. (2018). Pure bone marrow aspirate injection for chronic greater trochanteric pain syndrome: A case report. Pain Management, 8(4), 271–275.
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Chronic Greater Trochanteric Pain Syndrome
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Day, M. A., Hancock, K. J., Selley, R. S., Olsen, R., Ranawat, A. S., Nwachukwu, B. U., Kelly, B. T., & Nawabi, D. H. (2022). Hip arthroscopy with bone marrow aspirate injection for patients with symptomatic labral tears and early degenerative changes shows similar improvement compared with patients undergoing hip arthroscopy with symptomatic labral tears without arthritis. Arthroscopy.
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Pintore, A., Notarfancesco, D., Zara, A., Oliviero, A., Migliorini, F., Oliva, F., & Maffulli, N. (2023). Intra-articular injection of bone marrow aspirate concentrate (BMAC) or adipose-derived stem cells (ADSCs) for knee osteoarthritis: A prospective comparative clinical trial. Journal of Orthopaedic Surgery and Research, 18, Article 350.
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Marrow Cellution BMA + Adipose
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MSC's, Adipose-derived cells
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Easley, J. T., Sikes, K. J., Bisazza, K., Meyers, M., Stewart, H. L., & Reves, B. (Year). Preclinical evaluation of Marrow Cellution needle compared to traditional aspiration and BioCUE centrifugation system. Colorado State University, Department of Clinical Sciences.
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Marrow Cellution BMA vs. BioCUE centrifugation system
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Bone Marrow Cell Harvesting
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Sobti, A. S., Baryeh, K. W., Woolf, R., & Chana, R. (2020). Autologous matrix-induced chondrogenesis and bone marrow aspirate concentrate compared with microfracture for arthroscopic treatment of femoroacetabular impingement and chondral lesions of the hip: Bridging the osteoarthritis gap and facilitating enhanced recovery. Journal of Hip Preservation Surgery, 7(3), 503–510.
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Lutz, G. E. (2023). Intradiscal leukocyte-rich platelet-rich plasma for degenerative disc disease. Physical Medicine and Rehabilitation Clinics of North America, 34(1), 117–133.
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Degenerative Disc Disease
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Platelets, Luekocytes, HCT, RBC's, WBC's, More..
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