VelvetDBF™
100% Allograft DBF | Osteoinductive Potential | Excellent Handling | Rapid Rehydration | Osteoconductive Scaffold
VERSATILE, DEMINERALIZED BONE FIBERS WITH VERIFIED OSTEOINDUCTIVE POTENTIAL
key BENEFITS
Excellent Handling Without a Carrier
Provides a cohesive, moldable consistency that shapes easily, resists irrigation, and simplifies graft placement without the use of added carriers.
Verified Osteoinductive Potential
Demonstrates osteoinductive potential supported by in vitro and in vivo studies, including ALP testing and evidence of new bone formation..
Rapid Rehydration & Void Filling
Rapidly hydrates with blood, BMA, PRP, or saline and expands to retain fluid, conforming to patient anatomy and filling bone voids efficiently.
Osteoconductive Fiber Architecture
Provides a biologic scaffold to direct and support new bone formation.
SEM Imaging of VelvetDBF illustrates malleable elongated interwoven fibers, pore sizes of 100 μm+, and a rugged topography to support cellular infiltration and adhesion, and promote osteoconductivity.
Clinical applications
This graft is intended for homologous use in the repair, replacement, or reconstruction of osseous defects. This would include filling bone voids or gaps of the skeletal system.
Trauma/Oncology
- Non-unions
- Fractures
- Bone defects
- Tumor resection
Reconstruction
- Total joint surgery
- Revision joint surgery
- Fracture repair & reconstruction
Extremities
- Total joint surgery
- Revision joint surgery
- Fracture repair & reconstruction
Spine
- Cervical spine fusion
- Lumbar spine fusion
- Sacroiliac joint fusion
- Scoliosis
preparation & handling
Clinical Evidence
| Osteoinductive Activity of VelvetDBF™ | |||
|---|---|---|---|
| Analysis |
Sample N= |
Result (Average) |
Control / Threshold |
| Alkaline Phosphatase (ALP) Activity | 5 Donors | 1.46 | 0.2 (OI assay threshold) |
| BMP-2 Expression (ELISA) | 8 Donors | Statistically higher vs control | p < 0.001 |
| BMP-7 Expression (ELISA) | 8 Donors | Statistically higher vs control | p < 0.001 |
| In Vivo Osteoinductive (OI) Score | 12 Donors | ~2 | p < 0.001 |
Data derived from in vitro and in vivo testing, including ALP assays, ELISA quantification of BMP-2 and BMP-7, and an ASTM athymic nude rat model. Results demonstrate osteoinductive potential and are not intended to represent human clinical outcomes.
View the VelvetDBF™ Scientific White Paper for detailed methodology and preclinical evidence supporting osteoinductive potential. For the complete updated list contact us.
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Discover the clinical advantages of high-performance demineralized bone fiber.
